In our recent question and also answer, the pharmacist discusses whether or not Zyrtec (cetirizine) deserve to be safely taken with Claritin (loratadine).

You are watching: Can zyrtec and claritin be taken together


Johnn asked

Can you take it Claritin and Zyrtec simultaneously? will certainly there be much better effects?


Typically, that is not recommended to use loratadine(Claritin) and cetirizine (Zyrtec) at the exact same time. Both medications aresecond-generation antihistamines offered for allergy relief. Acquisition them with each other would not administer much added benefit,but could lead to side results such as drowsiness.

In part patients,Zyrtec may work far better than Claritin, however, it likewise may also causedrowsiness. Zyrtec, Claritin, and also Allegra space second-generationantihistamines and also are still much less likely to reason drowsiness thanfirst-generation antihistamines such together Benadryl (diphenhydramine). This isbecause first-generation antihistamines overcome the blood-brain barrier, whereasthe second-generation antihistamines usually carry out not.

Flonase together An Alternative

Instead of taking Claritin and also Zyrtec together, another option would certainly be to switch or include fluticasone(Flonase) nasal spray. Flonase was approved by the FDA in 1990, yet has onlybeen accessible over-the-counter because 2014. Flonase is a form of steroid thatblocks inflammation, itching, and also congestion.

According to the Flonase website, it has some advantages over Claritin, including working better for sleep congestion. Flonase have the right to be offered once dailywith 1 or 2 sprays right into each nostril or might be provided as needed rather of everyday.

Flonase deserve to safely it is in paired v an antihistamine.

How Antihistamines Work

Antihistamines tie to histamine receptors the are uncovered inthe nose, lungs, eyes, and skin there is no activating the histamine response. Bybinding and an altering the shape of the histamine receptor, antihistaminesinhibit histamine indigenous binding and also creating that is response. Histamine creates animmune response to essentially attempt to eliminate the offensive allergen.

See more: Can You Own A Gun In Dc Concealed Carry Gun Laws: Reciprocity

Histamine can be motivated by a variety of things includingpollen, dust, and also pet dander. Some people are an ext sensitive to this responseand might not also know what triggers your allergies. Antihistamines room usefulin avoiding the immune cascade so common in people suffering native allergies.


To conclude, that is not recommended to take both Claritin andZyrtec together because of the possibility of drowsiness without added benefit.Flonase sleep spray might be another option to administer an alternate mechanismof action against allergies.