Medically the evaluation by Alisha D Sellers, Pharm D, BS Pharmacy — composed by Aaron Kandola on august 17, 2021

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It have the right to reduce inflammation and also ease several symptoms, consisting of pain and fever. That is for sure for civilization with COVID-19 to take it — over there is no proof that ibuprofen rises the risk of damage from COVID-19 or the vaccines that protect against this disease.


COVID-19 can cause a wide range of symptoms, including fever, ill throat, and also loss that taste or smell. Over-the-counter medications, such together ibuprofen, can aid treat these symptoms.

There to be initial concerns around the safety and security of people with COVID-19 acquisition ibuprofen, however these insurance claims originated from anecdotal and also low-quality evidence. Significant public health and wellness bodies roughly the people do not advise against using ibuprofen to lull COVID-19 symptom or the side results of the vaccine.

Keep reading to learn much more about the initial safety and security concerns about taking ibuprofen v COVID-19 and also the proof surrounding the use of the drug v this condition.

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Stay educated with live update on the existing COVID-19 outbreak and also visit ours coronavirus hub for more advice top top prevention and also treatment.


Is it for sure to take it ibuprofen v COVID-19?

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The Centers for condition Control and also Prevention (CDC) suggest taking medications, consisting of ibuprofen, for treating COVID-19 exterior of the hospital.

The world Health organization (WHO) additionally states over there is no proof of major side effects from taking ibuprofen in human being with COVID-19. However, the examine that aided the organization draw this conclusion did not involve direct evidence from individuals with COVID-19.

Despite the latest guidance, there were initial concerns over the security of human being with COVID-19 taking ibuprofen.

Learn about safe dosages of ibuprofen.


Why did people think it to be dangerous previously?

A 2020 file suggested that SARS-CoV-2, the virus that reasons COVID-19, affect the body v angiotensin convert enzyme 2 (ACE2). ACE2 is one enzyme that impacts bodily processes such together blood pressure.

Ibuprofen is an NSAID, among the most common drugs for treating a range of health conditions. They alleviate inflammation in the body, a procedure that contributes to plenty of diseases, consisting of COVID-19.

Taking ibuprofen can increase ACE2 level in the body. This connection led come the concept that the drug can increase the danger of occurring COVID-19 or worsen the symptoms. Leading clinical journals, including The British medical Journal, additionally published files suggesting feasible risks the NSAIDs.

Major public health bodies additionally urged caution on utilizing NSAIDs in civilization with COVID-19, including the WHO. However, health experts based these decisions ~ above anecdotal or low-quality experimental evidence, and also there continues to be no proof to support this theory.

For example, the WHO performed a substantial review the 73 clinical trials top top the safety and security of NSAIDs for people with COVID-19 in 2020. The researchers uncovered no proof of a link in between taking NSAIDs and severe side effects, lessened recovery times, or fatality in world with the disease.

A much more recent 2021 research in The Lancet Rheumatology check data from 72,179 civilization from 255 medical care facilities throughout the joined Kingdom. They uncovered no evidence of one association in between NSAID use and a higher risk of fatality or more severe condition in those through COVID-19.

All data and also statistics are based upon publicly available data at the time of publication. Some information may be out of date. Visit our coronavirus hub and follow our live updates page because that the many recent information on the COVID-19 pandemic.


There is no evidence that ibuprofen deserve to worsen the symptom of COVID-19.

There were initial comes to that this drug could worsen COVID-19 symptom by enhancing ACE2 levels. The theory declared that greater amounts of ACE2 might assist SARS-CoV-2 in attacking healthy cells roughly the body. However, there is quiet no proof to assistance this.

Doctors may recommend taking NSAIDs to enhance the symptoms of COVID-19, such together fever. Medical care professionals additionally suggest taking ibuprofen for comparable conditions, such as influenza. Additionally, the drug deserve to alleviate other COVID-19 symptoms, such together muscle aches and also pains.


The recommended therapies for COVID-19 count on its severity and also a person’s in its entirety health.

Ibuprofen or acetaminophen

Some treatment philosophies aim to minimize pain and also discomfort. Because that example, doctors might recommend ibuprofen or acetaminophen (paracetamol) together a pain reliever for COVID-19.

Learn more about ibuprofen, acetaminophen, and their differences.

Remdesivir

Other treatment approaches aim to minimize pain by slowly the virus or an illness progression.

The Food and also Drug management (FDA) has actually approved remdesivir, an antiviral medication, for dealing with COVID-19.

Hospital treatment

Doctors may administer different treatments in patient in the hospital through COVID-19, such as blood thinners.

Learn much more about what hospital treatment could involve for human being with COVID-19.


The CDC recommends talking with a doctor about taking ibuprofen to aid with the side results of the COVID-19 vaccine. NSAIDs, such as ibuprofen, might reduce some side effects, such as fever, chills, or muscle aches.

However, the firm advises versus taking ibuprofen prior to getting the vaccine to prevent its side effects.

Side impacts of the vaccine

The COVID-19 vaccines can reason side effects, together with any medication. However, these are commonly mild and also resolve within a few days. The side impacts can include:

pain, purged skin, and swelling in ~ the injection sitetirednesshead and muscle acheschillsfevernausea

It is essential to keep in mind that severe or long-lasting side effects from the COVID-19 vaccine are incredibly rare.

Learn much more about remedies because that potential vaccine side effects.

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There is right now no evidence that taking ibuprofen have the right to increase the danger of developing COVID-19 or worsening symptoms. There is likewise no research stating that ibuprofen boosts the threat of fatality from COVID-19 or complications following the vaccine.

There were initial concerns over the safety and security of acquisition ibuprofen through COVID-19 as result of its impact on ACE2 levels in ~ the body. However, this theory still lacks evidence. NSAIDs help people regulate some COVID-19 symptoms and also vaccine side effects, such as fever.