Benadryl is a widely used medication for dealing with allergy symptoms, yet it can reason problems when mixed with alcohol.

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Benadryl is the brand surname for one antihistamine known as diphenhydramine. The medicine helps to minimize allergy symptoms, including rashes and coughs and also irritated eyes, throat, and nose.

While the does not affect on the liver, Benadryl is a main nervous device (CNS) depressant, the very same as alcohol. Once it is taken through alcohol, the combined impact on the CNS can produce heightened side effects. In part situations, this interaction deserve to produce very dangerous results.


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Share top top PinterestBenadryl is a brand of antihistamines typically used because that allergies.
Benadryl can cause side effects, consisting of sedation and drowsiness, which dilute coordination and also reaction speed.

Mixing Benadryl with alcohol deserve to intensify these side effects and will impair a person’s day-to-day functioning.

This have the right to be life-threatening if the involves specific activities, such together driving or operating hefty machinery.

2. Loss of consciousness

Some human being are an ext prone than others to losing consciousness as soon as sedated. In these people, combining Benadryl and alcohol is an ext likely to reason a loss of consciousness. This can be harmful as result of the likelihood of falls and other accidents.

3. Dehydration

Benadryl and also alcohol are both recognized to dehydrate the body. Mixing them deserve to increase the hazard of dehydration. This can cause discomfort in ~ the time and also may worsen a hangover.

4. Symptom in enlarge adults

Aging slowly the body’s capability to malfunction alcohol so the it may stay in the system of an larger adult for much longer than someone younger. This slowdown increases the time a person will it is in at danger of a harmful interaction between Benadryl and alcohol.

5. Learning and memory impairment

Benadryl block the action of a neurotransmitter dubbed acetylcholine. Acetylcholine is important for learning and memory, so blocking its action may temporary impair these processes.

Alcohol is additionally known to inhibit learning and memory temporarily. So, combine alcohol and also Benadryl may again have a much more noticeable impact on learning and also memory.

6. Interactions through other varieties of medication


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Share ~ above PinterestBenadryl may connect with cough and also cold medication.
Benadryl may interact with other species of medication, which deserve to heighten the side effects.

Taking these other species of drugs with alcohol could additionally increase the danger of side effects.

Examples of medications that may interact with Benadryl include:

stomach ulcer medicinecough and also cold medicineother antihistaminesdiazepam (Valium)sedatives

7. Various other sources the alcohol

Some varieties of medication, including cough syrup and laxatives, additionally contain alcohol. They can encompass up to 10 percent alcohol, which may communicate with Benadryl.

As a consequence, taking Benadryl v these medicines when spend very little amounts of alcohol may still increase the danger of adverse side effects.

8. Sex

In general, females are an ext susceptible come alcohol-related harm. This is since their bodies typically contain much less water for alcohol to mix with, definition that the same amount the alcohol would certainly be more concentrated in a female 보다 in a male.

Mixing Benadryl v alcohol may be an especially hazardous for females, as consuming smaller quantities of alcohol could trigger adverse interaction effects.

9. Misuse

As Benadryl and also alcohol both cause drowsiness and sedation, it might seem tempting to make use of this mix as a sleeping aid. However, this can also heighten other adverse side impacts that will interfere with sleep, such together nausea and dizziness.

10. Dementia


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Share top top PinterestMore studies are compelled to recognize if mixing Benadryl and alcohol causes dementia.
One study found that human being who take one anticholinergic medicine per day because that at the very least 3 years have actually a elevated risk the dementia. It need to be provided that this study had all anticholinergic drugs, not simply Benadryl.

Another study in 2018 found excessive alcohol usage to be connected with a higher risk of dementia. It is feasible that consuming large amounts that Benadryl and also alcohol over lengthy periods of time might be connected to an boosted risk that dementia.

However, longitudinal research study would be compelled in human being who consume high levels of Benadryl and also alcohol to know whether this has any effect ~ above the risk of dementia.


The risks associated with mix Benadryl and alcohol may not use to everyone or every situation. That is possible that consuming little amounts that alcohol while acquisition Benadryl in a safe setting will reason no harm. However, the safest option is simply to abstain from alcohol while acquisition Benadryl.

Under no circumstances need to Benadryl and also alcohol it is in mixed prior to engaging in any activity that required mental alertness, such as driving.

If who else has either purposely or unintentionally mixed Benadryl with alcohol, it is necessary to ensure they room in a safe environment, whereby they have the right to rest, if require be.

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It is ideal to consult with a physician to identify when it would certainly be safe to consume alcohol after acquisition Benadryl, as this will depend on other factors, such as period or various other courses of medication.