Postorgasmic condition syndrome may sound prefer hypochondriac bullshit, but it is an extremely real – and apparently turns sufferers into zombies every time castle orgasm.

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A couple of weeks ago, ~ above an illustration of the long-running brothers comedy panel show QI, hold Stephen fried food stumped the contestants through a question around postorgasmic illness syndrome, or POIS. ~ sex, fry claimed, patient report "flu-like symptoms, rashes, itching, exhaustion, and concentration difficulties."

"It wake up to men, and also it's thought to be the an outcome of being allergic come your own semen," fry said, setup off mine bullshit alert a little. Then he added that the cure is "multiple subcutaneous injections the your very own semen."


I'm no expert, however I've busted one ejaculation myth or 2 in mine time, and all of this sounded choose insane, superstitious bullshit.

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But together it turns out, that isn't. "Yes you deserve to be allergic to your own semen," Dr. Richard Santucci, head of urology in ~ Detroit Receiving Hospital, told in an email, "and yes the treatment might be semen injections."

In reality, POIS is a rare yet recognised clinical condition. The was found in 2002 in the Netherlands, and also far from gift the hilarious real-life Farrelly brother movie it sounds like, it reportedly reduces sufferers to zombie for around a main after one orgasm. Follow to a file on the syndrome, composed by POIS discoverers Marcel Waldinger and also Dave H. Schweitzer, "the symptoms space so severe that sexual task is avoided."

A guy mentioned in a 2013 Egyptian case study is report to have had "a solid desire and also rigid erections," and even controlled to have actually kids, yet his POIS symptom worsened v age, and also he even showed symptoms as soon as he had a "nocturnal emission" (a.k.a. A wet dream). In other words, when coming provides someone the flu, that person eventually tries to prevent coming, yet even that doesn't prevent the nightmare.

As you could expect, the syndrome also has its very own subreddit whereby sufferers exchange stories and also attempt come diagnose one another. One anonymous user over there sounds quite desperate, relenten POIS together a short-lived mix in between depression and delirium: "It's simply like having actually your heart sucked out of you," that wrote, adding, "your brain won't job-related well, and also you're simply kind of slow."


That user reported gift diagnosed through "severe depression motivated by orgasm," yet said he was not satisfied v the diagnosis, nor the therapies for it. "If friend have any suggestions as to what rather I might try, even if it is it's a various branch that medicine, some type of certain drug/treatment, or woo-woo voodoo alternate medicine, I'm interested to hear it," that wrote.

In 2011, Waldinger emerged an explanation because that POIS, and also a particular kind the treatment: He came to be convinced that it to be an allergy come one's very own semen. Waldinger learned 47 afflicted men, and also reasoned the they "didn't feeling ill as soon as they masturbated without ejaculating, but as soon as the semen come from the testes…after that they came to be ill, periodically within just a couple of minutes," leading him to conclude the difficulty must it is in the semen itself. Skin tests were administered, and 88 percent that the afflicted comment positively.

After reviewing the study, Santucci, the Detroit The evidence for the allergy hypothesis is quite striking, follow to Santucci, of the Detroit Receiving Hospital. He compared it come a recognized allergy come semen in women. "Women most often have quality irritation however a notable few have systemic flu-like symptoms, and also a rare couple of have perhaps deadly anaphylaxis," he said.

The treatment, according to Waldinger: injections of incredibly diluted semen under the skin, designed to cause a little amount the the reaction, through the concentration that semen increased over end a duration of between one and also three years, through the goal of eventually achieving a reduction in symptoms.


Santucci again contrasted this come a similar treatment regimen for women v diagnosed semen allergies. "Less serious cases can it is in desensitised v unprotected sex end time, but may require injections that the partners semen," he wrote in an email.

You might want to think double if you're considering semen therapy at home, though. "If girlfriend are very allergic this deserve to kill you," follow to Santucci.

But research that characteristics POIS symptoms to semen allergy is no yet definitive, and there are different theories. Previously this year, medical professionals in China recorded the very first known instance of POIS in that country. The patience was offered a skin test, yet so were three "healthy" subjects with no POIS symptoms. Lock all had positive reaction to the skin test, arguing that false positives may have been rampant in Waldinger's research.

There space other possible explanations. One document brings up hormone problems and also hyperglycemia as possible causes that POIS. A 2010 document in the newspaper of sexual Medicine suggests POIS may be resulted in by a "spectrum" the illnesses, each requiring separate clinical attention.

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A reliable answer seemingly can't come soon enough for the Redditor who has written in ~ length around his affliction. It sounds prefer he's obtained it nice rough. "My sex-related experience has actually been incredibly limited, however the just time i orgasmed v a girl, unsurprisingly, ns just got really scramble-brained and pretty much had to leave ASAP. That was quite embarrassing," the wrote.