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What is Epigenetics? • C. H. Waddington coined the term epigenetics come mean over or in enhancement to genes to describe differentiation. • how do various adult stem cells recognize their fate? o o Myoblasts can only form muscle cell Keratinocytes only kind skin cells Hematopoetic cell only come to be blood cells but all have identical DNA sequences. • Modern definition is non-sequence dependence inheritance. • How have the right to identical pair have various natural hair colors? • How deserve to a single individual have two various eye colors?




You are watching: Can identical twins have different hair color

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Mosaicism: one Individual through Two different Eye colors “Diego”


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Mosaicism: An separation, personal, instance Eye v Two colour


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What is Epigenetics? • C. H. Waddington coined the term epigenetics come mean over or in addition to genes to describe differentiation. • just how do various adult stem cells recognize their fate? o o • • Myoblasts have the right to only type muscle cells Keratinocytes only form skin cell Hematopoetic cells only come to be blood cells but all have actually identical DNA sequences Modern definition is non-sequence dependence inheritance. How have the right to identical twins have different natural hair colors? How have the right to a single individual have actually two various eye colors? How deserve to identical twin liter mates show various coat colors?


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Coat colour of Genetically identical Agouti mice Liter Mates


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What is Epigenetics? • C. H. Waddington coined the ax epigenetics to mean over or in enhancement to genetics to explain differentiation. • just how do various adult stem cells know their fate? o o • • • Myoblasts can only type muscle cell Keratinocytes only type skin cells Hematopoetic cells only become blood cells but all have identical DNA sequences. Modern meaning is non-sequence dependency inheritance. How deserve to identical pair have various natural hair colors? How have the right to a solitary individual have two various eye colors? How have the right to identical pair liter mates show different coat colors? How can just head or maternal traits be expressed in offspring? This is dubbed genetic imprinting. • How have the right to females express only one X chromosome every cell? • how can obtained traits be passed on come offspring? • Some transforms in gene expression that are, in fact, heritable!


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DNA Methylation & the Epigenetic password Paula Vertino, Henry Stewart speak




See more: Bubble, Bubble, Toil And Trouble, Song Of The Witches: “Double, Double Toil And…

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DNA Methylation & Histone Modifications kind the Epigenetic code Paula Vertino, Henry Stewart speak


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Cytosine Methylation Maintains Inactive-Condensed chromatin State Transcription determinants RNA polymerase transcription Acetylation DNA methyltransferase Methyl-Cp. G Binding proteins and associated co-repressors 5 -methyl-C Histone deacetylase transcription blocked X Deacetylation chromatin compaction Transcriptional silencing Alex Meissner, Henry Stewart talks