Aches and fever are common side effects of coronavirus vaccination. But will taking acetaminophen or ibuprofen impact how well the vaccine works?The next effects present that the vaccine is teaching your immune system just how to recognize and also attack SARS-CoV-2, the coronavirus that reasons COVID-19, if it encounters it.

You are watching: Can i take motrin after moderna vaccine

Experts say perform not take it pain relievers prior to your vaccine.

All data and statistics are based on publicly available data at the time of publication. Some info may be out of date. Visit ours coronavirus hub and follow our live updates web page for the most recent info on the COVID-19 pandemic.

The coronavirus vaccine helps safeguard you from gaining COVID-19. The can additionally prevent girlfriend from having the long-lasting health problems experienced by part COVID-19 patients, or “COVID-19 long haulers.”

As with all vaccines, friend may have actually some next effects, such as pain or ede at the site of the injection, fever, chills, tiredness, or headache.

Dr. David J. Cennimo, one infectious disease physician and also assistant professor at Rutgers new Jersey medical School, claimed these room “signs the an suitable recognition and also immune reaction to the vaccine.”

The side effects display that the vaccine is teaching your immune system how to recognize and also attack SARS-CoV-2, the coronavirus that causes COVID-19, if the encounters it.

Although several of the vaccine side effects are comparable to the symptom of COVID-19, the coronavirus vaccines won’t give you COVID-19. The vaccines will also not make you contagious.

For many people, the side impacts of the vaccine room mild or moderate and also last only a work or two. However, because that some people the side results make lock feel favor they have the flu, or impact their capability to perform daily activities.

Faced through a couple of work of flu-like discomfort, many human being — including physicians — will certainly reach because that an over-the-counter medicine such together ibuprofen (Advil, Motrin) or paracetamol (Tylenol) to relax their fever and pain.

But if these drugs minimize the side effects of the vaccine, is over there a chance that they’ll also depress the immune system’s beneficial solution to vaccination?


No research has actually been done to look particularly at whether acetaminophen or ibuprofen can interfere with how well the coronavirus vaccine works.

But Cennimo said some earlier research says that part drugs may affect the immune solution to vaccines.

“There room data in the vaccine literature, long predating COVID-19 and nearly all in children, the premedication v choose acetaminophen or ibuprofen to decrease the antibody an answer to the an initial dose of vaccine,” Cennimo said.

Parents would sometimes provide their child a pains reliever prior to their vaccine injection come head turn off the discomfort.

Cennimo stated it’s no known how these medications interfere with vaccines, but the drugs might dampen the inflammatory response — which reflects up as fever and also aches.

With much less inflammation, that said, there may additionally be a reduced immune an answer to the vaccine.

More recently, a study released this month in the journal of Virology discovered that nonsteroid anti-inflammatory drugs (NSAIDs) — which incorporate ibuprofen — diminished the manufacturing of antibodies and other elements of the immune solution to SARS-CoV-2.

Antibodies are proteins made by the immune mechanism to fight viruses choose SARS-CoV-2. The COVID-19 vaccines wake up the human body to create antibodies that specifically target the coronavirus without causing disease.

The writer of this study stated that this raises the possibility that NSAIDs might also influence the immune an answer to coronavirus vaccination. But additional studies would certainly be necessary to recognize for certain.

Some previously research in the laboratory argues that fever-reducing pain medications might blunt the antibody response to vaccination, but it’s not clear what this way in the genuine world.

More research is needed, the course. But COVID-19 vaccine researches that have already been done imply that acquisition a pains reliever after ~ injection, if needed, might not cause that lot of a problem.

The protocols for the late-stage clinical trials that the Pfizer-BioNTech and also Moderna-NIAID coronavirus vaccines didn’t prevent human being from acquisition pain-relieving drugs if lock felt they required it.

Even with that, those researches still verified that both vaccines have actually a high efficacy rate: 95 percent for Pfizer-BioNTech and also 94.1 percent because that Moderna-NIAID.

In spite of the require for more data, Cennimo doesn’t think there’s a difficulty with acquisition ibuprofen or acetaminophen after your coronavirus vaccine injection, as long as you don’t exceed the recommended amount.

He had actually his 2nd dose of the coronavirus vaccine last week and also took ibuprofen after that for a low-grade fever and some aches.


As because that whether you should shot to preempt your vaccine side results with a pains reliever, Cennimo advises against it.

“In the COVID-19 vaccine trials, human being were not offered an NSAID or acetaminophen before the injection, therefore we carry out not recognize what — if any type of effect — premedication would have,” that said. “Because of these theoretical risks, the is not advised.”

Cennimo claimed the pre-COVID-19 vaccine research in children found that acquisition a fever-reducing medicine only impacted the production of antibodies if the drug was taken prior to the injection.

Dr. Sherrill Brown, clinical director the infection avoidance at AltaMed health and wellness Services, a federally qualified healthcare facility serving Los Angeles and also Orange counties in California, agrees.

“I would certainly recommend waiting till someone experiences side impacts of fever or pains that require fever-reducing or pain-reducing medications,” she said, “and no to take them as a prophylaxis to protect against vaccine associated symptoms.”

The Centers for condition Control and also Prevention (CDC) issued similar guidelines for exactly how to resolve the side results of the two mRNA vaccines that have actually been approved in the joined States.

Brown likewise cautions that even over-the-counter pains relievers may not be suitable for everyone.

“Some world are no able to take either acetaminophen or ibuprofen because of other underlying health conditions,” she said. “In those cases, it would be best to consult through their trusted medical care provider or physician prior to taking these medications.”

If you can’t take it pain relievers, or friend would prefer to avoid taking castle after her coronavirus vaccine injection, there space other ways to relieve inoculation side effects.

To minimize pain and discomfort at the website of injection, apply a cool, wet washcloth end the area to alleviate the swelling. Gently working out the arm likewise increases blood flow to the area which have the right to provide additional relief.

For fever, drink lot of of fluids, wear irradiate pajamas or clothing, sponge your body with lukewarm (not cold) water, and also eat popsicles. And of course, rest.

See more: Can Migraines Be A Sign Of Pregnancy & When To Test, Headaches In Early Pregnancy

If your heat lasts much longer than 3 days, or will 103°F (39°C) or higher, seek clinical care. Look for treatment right away if you build a rash, an obstacle breathing, or chest or abdominal pain.